Proton Pump Inhibitors (PPIs) suppress acid production in the stomach. Accurate dosing can be very tough to estimate, and excessive use can lead to poor digestion of food and longer term health problems.
PPIs aim to shut down gastric acid production in the stomach by direct inhibition of the proton pump. The only PPI licensed for horses in the U.S. is omeprazole, marketed as Gastro Guard®.
Drugs have many shortcomings, and proton pump inhibitors have some unique ones. When your horse builds a tolerance after prolonged daily use, you find yourself continually increasing the dosage to achieve the same results.
These side effects are very accurately described in the PDR/Physician’s Desk Reference for humans, as these drugs have been used for humans much longer than for horses.
Other studies list other common side effects for these types of acid blocking drugs such as: abdominal pain, diarrhea, headache, nausea and vomiting.
Less common effects you could experience include; abdominal swelling, aggression, anemia, anxiety, apathy, back pain, blood in urine, changes in liver function, chest pain, confusion, constipation, cough, depression, difficulty sleeping, discolored feces, dizziness, dry mouth, dry skin, fatigue, fever, fluid retention and swelling, fluttery heartbeat, frequent urination, gas, general feeling of illness, hair loss, hallucinations, hepatitis, high blood pressure, hives, irritable colon, itching, joint and leg pain, loss of appetite, low blood sugar, muscle cramps and pain, nervousness, nose bleeds, pain in testes (!), rapid heartbeat, rash, ringing in ears, sleepiness, slow heartbeat, stomach tumors, upper respiratory infection, urinary tract infection, vertigo, weakness, weight gain and yellow eyes or skin. Just what you want in a reliable mount-NOT!
The driving factors that lead to a horse suffering from excessive digestive acidity in the first place are not addressed when solely using these drugs. Re-evaluate your feed program, and water quality, if you are considering use of PPI drugs.
Equine Ulcers & Colic in Horses
Nutrient Buffer® is versatile enough to be used daily for horses in every walk of life. With drugs like H₂ Blockers and Proton Pump Inhibitors (PPIs), the body can build a tolerance and require higher dosages over time, while Nutrient Buffer® works the same all the time, every time - with the added benefit of helping resolve colic situations when you need it the most.
Since Marion Dupont-Scott did their classic ulcer study decades ago, showing that race horses tend to dump a lot of stomach acid at the break from the gate, Nutrient Buffer® has been one of the most widely used digestive aid buffering supplements for horses prior to stressful conditions. According to many prominent race track veterinarians, it helps horses race better.
Whether your horse is injured or ill and in recovery, ulcers are known to become a problem in stalled and confined horses. Horses are grazers and designed for continuous movement to aid their digestion and well being.
Nutrient Buffer® has been demonstrated to aid horses with anemia by reducing the binding of iron to lactoferrin and releasing it into the blood and tissues.
A gastric ulcer is essentially a sore on the wall of the stomach, duodenum or even hind gut/large intestine. It is caused by excessive acid secretion by the stomach when there is either no food in the stomach to absorb the acid, or a stimulated excess secretion of acid due to stressful conditions that the horse is under.
Excess acidity and diet problems can provoke a colic attack. Race track veterinarians both use and recommend Nutrient Buffer® as a first approach in colic cases, often eliminating the need for costly surgery. It is the "original" natural digestive aid buffering supplement that helps soothe the gut, and aid in relaxation so the impaction can pass.
The original U.S. patented liquid digestive supplement. 100% USP grade ingredients, drug-free, with over 20 years of success and reliability.